Qsymia (Phentermine and Topiramate)
July 17, 2012 the FDA approved a new drug Qsymia for obesity treatment. The new drug Qsymia for obesity treatment consists of two pharmacological substances Phentermine and Topiramate.
- Phentermine was approved by the FDA for short therapy of exogenous obesity.
- Topiramate was approved by the FDA for the treatment of epileptic attacks and prevention of migraine.
Feasibility of combined use of Phentermine and Topiramate is proven by the fact that Topiramate has anorexigenic effect just as Phentermine. Therefore Topiramate increases pharmacological action of Phentermine, allowing to reduce the dose of Phentermine twice.
It should be noted though that Topiramate possesses slight anorexigenic effect and even maximal Topiramate doses provide no significant effect. Hence, Topiramate cannot be prescribed for monotherapy of obesity and can be only used in combination with Phentermine.
Low doses of PPP in Qsymia anti-obesity drug helps to minimize the risk of side effects. But because of the lack of information on post-marketing trials, Qsymia anti-obesity drug (Topiramate, Phentermine) is not so popular in clinical practice so far.
Qsymia weight loss drug is produced in capsules for oral intake, in wide range of doses.
- Initial dose of Qsymia (Phentermine 3.75mg and Topiramate 23mg)
- Minimal therapeutic dose of Qsymia (Phentermine 7.5mg and Topiramate 46mg)
- Average dose of Qsymia (Phentermine 11.25mg and Topiramate 69mg)
- Maximal dose of Qsymia (Phentermine 15mg and Topiramate 92mg)
Qsymia capsules contain the active pharmaceutical substances Phentermine and Topiramate and also some additional ingredients:
Indications for use of Qsymia (Phentermine and Topiramate)
Qsymia slimming pills must never be taken in: glaucoma; hyperthyroidism; thyroid dysfunction; heart failure; simultaneous use with MAO inhibitors; allergic reaction to Phentermine and (or) Topiramate; allergy to inactive ingredients (from composition of Qsymia).
Pregnancy is a serious contraindication for use of Qsymia pills (Phentermine and Topiramate). Some data confirms that Qsymia increases the risk of rhagades (cleft lip, cleft palate).
Therefore women of reproductive age are recommended to avoid using Qsymmia slimming pills (Topiramate and Phentermine) during pregnancy or avoid getting pregnant if they are already using the pills. It is recommended to use some effective birth control pills while using Qsymia weight loss pills (Phentermine and Topiramate).
Side effects of Qsymia (Phentermine and Topiramate)
The most common side effects when using weight loss Qsymia, are: dizziness, tingling in hands and feet, change of taste sensations, insomnia, dry mouth and constipation.
Use of Qsymia (Phentermine and Topiramate)
- Qsymia weight loss pills (Phentermine and Topiramate) should be taken along with diet therapy and complex of exercises.
- It is recommended to take Qsymia pills (Phentermine and Topiramate) once a day on empty stomach or with food.
- You should stop taking Qsymia weight loss pills (Phentermine and Topiramate) by gradually reducing the daily dose. Sharp termination of Qsymia therapy increases the risk of seizures.
Safety use of Qsymia diet pills (Phentermine and Topiramate)
Efficiency and safety use of Qsymia weight loss pills (Phentermine and Topiramate) was proven by the results of randomized studies, involving about 4,000 patients with excess body mass and concomitant diseases.
According to results of those clinical trials, after a year of regular use of Qsymia in minimal dose (Phentermine 7.5mg and Topiramate 46mg), patients managed to lose up to 10% of their initial weight.
It was also proven that if 12 week after the daily use of Qsymia weight loss pills, the weight loss is at least 3% of the initial, it is no longer necessary to take Qsymia pills.
The FDA obliged the manufacturers of Qsymia slimming pills (Vivus, Inc. Company) to spend 10 years for marketing studies. In addition, the company was obliged to study impact of a long-term use of Qsymia weight loss pills (Phentermine and Topiramate) on the cardiovascular system.
Such decision of the FDA was based on the fact that long-term use of Phentermine medication (even in minimal doses) increases the risk of dysfunction in the cardiovascular system.
If you decided to buy Qsymia capsules but in your city this anti-obesity drug is no longer available, you can order Qsymia capsules on our online pharmacy. In order to buy weight loss drug Qsymia online, you will be offered to choose on your own one of the payment and shipping variants.